New susceptibility loci for nasopharyngeal carcinoma

Researchers identify three new susceptibility loci for nasopharyngeal carcinoma in the genome-wide association study they've published in Nature Genetics. The team examined 464,328 autosomal SNPs in 1,583 cases and 1,894 controls, and found that TNFRSF19, MDS1-EVI1, and the CDKN2A-CDKN2B gene cluster were associated with NPC. "Our findings provide new insights into the pathogenesis of NPC," the authors write.

References

- A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Jin-Xin Bei, Yi Li, Wei-Hua Jia, Bing-Jian Feng, Gangqiao Zhou, Li-Zhen Chen,Qi-Sheng Feng, Hui-Qi Low, Hongxing Zhang, Fuchu He, E Shyong Tai, Tiebang Kang, Edison T Liu, Jianjun Liu & Yi-Xin Zeng. [Nature Genetics->http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.601.html#a1] (2010)